ZDG Vibrating Fluid Dryer for Pharmaceutical and Herbal Processing: Mannitol Crystals
ZDG Vibrating Fluid Dryer is evaluated for mannitol crystals in pharmaceutical and herbal processing. The defined feed is washed aqueous-wet mannitol crystals. Match this duty to the material checks below and the unchanged original equipment parameters.
Mannitol Crystals: Application and Process Requirements
For mannitol crystals, control attrition and verify the crystal form required by the excipient specification. Begin with washed aqueous-wet mannitol crystals and confirm how the incoming grade varies before defining the drying cycle.
Feed, Product Quality and Downstream Handling
| Review item | Mannitol Crystals |
|---|---|
| Defined feed | washed aqueous-wet mannitol crystals |
| Material-specific focus | control attrition and verify the crystal form required by the excipient specification |
| Product checks | moisture, assay, crystal identity and particle distribution |
| Downstream handling | contained hygienic transfer under the facility's excipient controls |
Material Movement and Drying Control
Include moisture, assay, crystal identity and particle distribution in the trial record. Fix the sampling locations and analytical methods before comparing trials; feed preparation and cooling can affect the measured result.
Drying Endpoint and Product Acceptance
After acceptance, arrange contained hygienic transfer under the facility's excipient controls. Review discharge, temporary holding and packaging exposure as part of the moisture-control plan.
Application-Specific Equipment Selection
ZDG Vibrating Fluid Dryer selection for mannitol crystals starts with Vibrating Fluid Bed Dryer requirements and the defined feed. Assess vibratory fluidized bed dryer and fluid bed drying together with granule drying; the continuous fluidized bed dryer duty must be demonstrated using representative material and the required finished-product specification.
Define contact materials, cleaning, containment and qualification for the actual formulation. This application description does not establish sterile service, solvent-rated construction or a validated pharmaceutical process.
View the ZDG Vibrating Fluid Dryer range and original equipment specifications
Technical References for This Application
Document the material-specific process and its acceptance criteria. FDA process-validation guidance.
Review the manufacturing controls applicable to the intended pharmaceutical use. FDA Q7 manufacturing guidance.
Define equipment suitability, cleaning and qualification requirements. FDA pharmaceutical equipment considerations.
Review the dust characteristics of the collected dry material. HSE combustible-dust guidance.
Review the thermal duty and utilities for the actual feed. U.S. DOE process-heat reference.
Equipment Reference Parameters
These are the ZDG Vibrating Fluid Dryer model specifications. The operating duty for mannitol crystals must be established from the feed and the finished-product requirements above.
| Model | Area of fluidized-bed (m²) | Temperature of air inlet (°C) | Temperature of air outlet (°C) | Capacity to vapor moisture (kg/h) | Vibration motor | Power (kW) |
|---|---|---|---|---|---|---|
| ZDG3×0.30 | 0.9 | 70~140 | 40~70 | 20~35 | YED10-6 | 0.75×2 |
| ZDG4.5×0.30 | 1.35 | 70~140 | 40~70 | 35~50 | YED10-6 | 0.75×2 |
| ZDG4.5×0.45 | 2.025 | 70~140 | 40~70 | 50~70 | YED16-6 | 1.1×2 |
| ZDG4.5×0.60 | 2.7 | 70~140 | 40~70 | 70~90 | YED16-6 | 1.1×2 |
| ZDG6×0.45 | 2.7 | 70~140 | 40~70 | 80~100 | YED20-6 | 1.5×2 |
| ZDG6×0.60 | 3.6 | 70~140 | 40~70 | 100~130 | YED20-6 | 1.5×2 |
| ZDG6×0.75 | 4.5 | 70~140 | 40~70 | 120~140 | YED20-6 | 1.5×2 |
| ZDG6×0.9 | 5.4 | 70~140 | 40~70 | 140~170 | YED20-6 | 1.5×2 |
| ZDG7.5×0.60 | 4.5 | 70~140 | 40~70 | 130~150 | YED30-6 | 2.2×2 |
| ZDG7.5×0.75 | 5.625 | 70~140 | 40~70 | 150~180 | YED30-6 | 2.2×2 |
| ZDG7.5×0.90 | 6.75 | 70~140 | 40~70 | 160~210 | YED30-6 | 2.2×2 |
| ZDG7.5×1.2 | 9 | 70~140 | 40~70 | 200~260 | YED40-6 | 3.0×2 |
| Model | Bed area (m²) | Inlet (°C) | Outlet (°C) | Evaporation (kg/h) | Motor | Power (kW) |
| ZDG3×0.30 | 0.9 | 70–140 | 40–70 | 20–35 | YZS8-6 | 0.75×2 |
| ZDG4.5×0.30 | 1.35 | 70–140 | 40–70 | 35–50 | YZS10-6 | 0.75×2 |
| ZDG4.5×0.45 | 2.025 | 70–140 | 40–70 | 50–70 | YZS15-6 | 1.1×2 |
| ZDG4.5×0.60 | 2.7 | 70–140 | 40–70 | 70–90 | YZS15-6 | 1.1×2 |
| ZDG6×0.45 | 2.7 | 70–140 | 40–70 | 80–100 | YZS15-6 | 1.5×2 |
| ZDG6×0.60 | 3.6 | 70–140 | 40–70 | 100–130 | YZS20-6 | 1.5×2 |
| ZDG6×0.75 | 4.5 | 70–140 | 40–70 | 120–170 | YZS20-6 | 2.2×2 |
| ZDG6×0.90 | 5.4 | 70–140 | 40–70 | 140–170 | YZS30-6 | 2.2×2 |
| ZDG7.5×0.60 | 4.5 | 70–140 | 40–70 | 130–150 | YZS30-6 | 2.2×2 |
| ZDG7.5×0.75 | 5.625 | 70–140 | 40–70 | 150–180 | YZS40-6 | 3.0×2 |
| ZDG7.5×0.90 | 6.75 | 70–140 | 40–70 | 160–210 | YZS40-6 | 3.0×2 |
| ZDG7.5×1.20 | 9.0 | 70–140 | 40–70 | 200–280 | YZS50-6 | 3.7×2 |
| ZDG7.5×1.50 | 11.25 | 70–140 | 40–70 | 230–330 | YZS50-6 | 3.7×2 |
| ZDG8×1.80 | 14.4 | 70–140 | 40–70 | 290–420 | YZS75-6 | 5.5×2 |
| Item | Project specification |
| Equipment | Vibration-assisted fluid bed dryer |
| Heating | Select for available utilities |
| Contact materials | Confirm chemical compatibility and cleaning needs |
| Controls | Define temperature, airflow and vibration monitoring |
| Dimensions | Select from the process duty and layout |
| Documentation | Confirm required drawings, manuals and inspection records |
Discuss Mannitol Crystals Drying
Send QUANPIN the incoming mannitol crystals specification, sample information and the required final product condition for an equipment review.
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