Pharmaceutical Equipment / GHL
GHL Series High-Speed Mixing Granulator for Pharmaceutical Wet Granulation
Model: GHL
Blend powders with binder, then form wet granules using an impeller and high-speed chopper.
Suitable for pharmaceutical powder blends requiring wet granulation.
Product Overview
GHL combines wet blending and granule formation in a single vessel.
Working Principle
The bottom impeller distributes binder through the powder. A side-mounted chopper breaks wet agglomerates into granules.
Key Features
- High-speed mixing and wet granulation in one processing stage.
- Configure the vessel, controls and accessories for the material duty.
Suitable Materials
- Powder blends compatible with binder-assisted granulation.
- Review moisture, solvent compatibility, thermal limits and final granule requirements.
Wide Range of Applications
Pharmaceutical granule preparation and compatible powder-processing applications. Confirm suitability using representative formulation trials.
Explore QUANPIN industry applications.
Technical Parameters
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| Specification | 5 | 10 | 20 | 50 | 100 | 150 | 250 | 300 | 400 | 600 | 800 | 1000 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Volume (L) | 5 | 10 | 20 | 50 | 100 | 150 | 250 | 300 | 400 | 600 | 800 | 1000 |
| Working Volume (L) | 3.5 | 7 | 14 | 35 | 70 | 105 | 175 | 210 | 280 | 420 | 560 | 700 |
| Batch Output (kg/batch) | 0.8–1.8 | 2–3.5 | 4–8 | 10–18 | 20–35 | 40–60 | 60–100 | 70–120 | 80–150 | 120–220 | 180–300 | 250–400 |
| Operating Time (min) | 7–10 | 7–10 | 7–10 | 7–10 | 7–10 | 7–10 | 7–10 | 7–10 | 7–10 | 7–10 | 7–10 | 7–10 |
| Mixing Speed (rpm) | 60–600 | 60–600 | 150–500 | 20–200 | 20–200 | 20–200 | 40–180 | 40–180 | 40–180 | 50–120 | 50–120 | 50–120 |
| Chopper Speed (rpm) | 1000–2900 | 1000–2900 | 1000–2900 | 1000–2900 | 1000–2900 | 1000–2900 | 1000–2900 | 1000–2900 | 1000–2900 | 1000–2900 | 1000–2900 | 1000–2900 |
| Agitator Power (kW) | 1.5 | 2.2 | 4.0 | 5.5 | 11 | 15 | 18.5 | 18.5 | 30 | 37 | 45 | 55 |
| Chopper Power (kW) | 0.75 | 0.75 | 1.5 | 2.2 | 4.0 | 4.0 | 5.5 | 5.5 | 7.5 | 11 | 11 | 11 |
| Compressed-Air Consumption (m³/min) | 0.4 | 0.4 | 0.4 | 0.4 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 |
| Compressed-Air Pressure (MPa) | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 | 0.4–0.6 |
Confirm the selected configuration in the approved technical documents before ordering.
Frequently Asked Questions
What does GHL do?
It mixes powder with binder and forms wet granules.
Which feeds are suitable?
Powder formulations compatible with the specified wet-granulation process.
How is a model selected?
Define batch size, binder addition, granule targets, cleaning and downstream drying.
Request Pricing & Specifications
Send your formulation, required batch output and process requirements to QUANPIN.
Application Review: Pharmaceutical Wet Granulation
Review wet granulation, high-speed mixing, binder addition and wet granule handling together. Confirm the interface between the mixing granulator and downstream granule drying using representative material trials.
For pharmaceutical process evaluation, consult FDA process validation guidance.
For an active-ingredient application, review the equipment and documentation topics in FDA Q7A guidance.
For pharmaceutical cleaning requirements, consult the FDA equipment and cleaning questions.
Review the actual powder characteristics using the HSE safe handling of combustible dusts.
Include moving-part access in the installation review using HSE work equipment and guarding guidance.
Discuss Your
Processing Requirements.
Share your material, particle-size target and processing rate with QUANPIN to discuss an equipment configuration.